It was a two-goal effort from Edinson Cavani, a goal in each half, that caried the South Americans within a victory of the semifinals.
Right then, here are the two starting sides, no major surprises in either of them.
And he managed to score a-not-too-shabby four games in the tournament.
"Germany's fate made it clear what can happen to any strong team".
"It's not just in this World Cup that they have not been conceding goals - it has been like that for the whole of 2018".
Uruguay not just focusing on Cristiano Ronaldo
And if Uruguay can lock out Ronaldo again and send European champions Portugal home, Godin will surely have a lot to do with it. However, they have lost their last three games in the World Cup knockout stages (1 goal scored, 5 conceded).
Some would call it the dark arts of football, but both Uruguay and Portugal know how to get the job done and they have no issues playing hard if that is what it takes to win.
Pepe's header was the first goal that Uruguay had conceded at this World Cup, but Oscar Tabarez's side recovered to secure a date with France in Nizhny Novgorod on Friday.
"Oscar Tabarez is the longest-serving worldwide manager".
Ronaldo was involved somewhat in Portugal's goal, even if he didn't come close to getting a touch on the cross.
Belgium go top ahead of England, Japan and Colombia advance
Yerry Mina thumped home the second-half header to secure a dramatic victory that catapulted the South Americans into the last 16. The centre-back, now at the World Cup with Senegal , believes the £88m (€100m) switch he is being linked with is mad.
Uruguay has been one of the best teams at the 2018 World Cup having won all three of their Group stage games. "If Ronaldo plays alone we will lose", Santos told reporters at the Fisht Stadium, where the Portugal skipper scored a hat-trick in a 3-3 draw with Spain during the group phase.
But the rugged and courageous Godin, who needed reconstructive dental surgery after having three teeth punched out in an aerial challenge with Valencia's goalkeeper earlier this year, has succeeded in muzzling Ronaldo on plenty other occasions at club level going back nearly a decade.
Uruguay is heading into their first matchup in the knockout phase riding on a wave of confidence, thanks to their defense not having not given up a single goal during their ideal run at the cup thus far.
Portugal will not change the way they play, which is quite one-dimensional and not particularly inspiring.
Portugal's route to the knockout stages was less straightforward and they had to survive a late scare against Iran to progress.
Ronaldo had one clean shot the entire 90 minutes and it came in the opening moments of the match, directly into the arms of Uruguay goalkeeper Fernando Muslera. It won't be pretty, but it will certainly be absorbing and probably just a little bit X-rated.
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After the ruling was issued on Thursday, brick-and-mortar stocks rallied while online retailers fell. He said the legislation would be tailored to fit within the Supreme Court ruling .
First real chance for Portugal! A win against Morocco after that improved Portugal's probability still further. The team is in great form and will have a tough competition against Portugal, which also happens to be in a great form.