Blues boss Maurizio Sarri has elected to leave the Belgium global at home as Chelsea keep one eye on continuing their 100% start to the Premier League season.
Sane tapped home Fernandinho's inviting cross inside two minutes before Silva smashed his 50th Premier League goal and Sterling completed the rout.
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And Lippi could not hide his bemusement at the decision, which saw Ronaldo break down in tears on the Mestalla pitch. It was feared that Ronaldo could be banned for more than one match if the incident was deemed to be violent conduct.
Midfielder Danny Drinkwater is not in the Europa League squad due to UEFA regulations.
"I spoke with the club and said that ideally I think that a pinch of quality is lacking in our central midfield for a certain type of play", Sarri said.
"He's a low-maintenance footballer, I think, Chelsea have done really well to hang onto him for the past couple of years", he said.
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The transfer window closes on Thursday, August 9 and Chelsea begin their Premier League campaign away at Huddersfield Town on August 11, before hosting Arsenal the following Saturday.
He made substitute appearances in the first two Premier League games and has scored five goals in his subsequent three starts, delighting the Blues faithful who feared he would make a summer switch to Real Madrid which never materialised. "The only thing I know is that (referee) Mike Dean was very good and the assistants were very good".
Sarri said to The Telegraph: "Eden Hazard told me that after the national team and after the match against Cardiff he was a little bit exhausted so I thought it was better to stay in Cobham, to have training and to rest".
"[Kevin] De Bruyne and [Mohamed] Salah were the best players last season, I'm talking over a four or five-year period if I think "who's the man?".
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Pellegrini spoke today ahead of the Chelsea game and revealed: "Marko finished with a problem in his knee, he has had some treatment, we will see if he is fit for Sunday". "But now I change my mind because maybe he is the best", said Sarri.