Asked what she will do if MPs reject her plan, she retorted: "We haven't had the vote yet.
We will be explaining to members of parliament why we believe that this is a good deal for the UK", May told reporters on the plane to the G20 summit in Argentina when asked if she had a back-up plan.
"It's not about me", said Mrs May.
"This is about what is in the national interest", she said.
"It's about delivering the vote to leave the European Union and doing it in a way that protects people's jobs and livelihoods and protects our security and our United Kingdom".
She does not wish to do that, because she fears it would make it far easier for her MPs to vote against her on December 11, because they would know their votes were conscience-salving protest votes, rather than deal-destroying and possibly government-wrecking extreme sabotage.
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"A few days before the vote in the House of Commons, it is becoming more and more clear that this deal is the best possible - in fact, the only possible one".
"If this deal is rejected in the Commons, we are left with.an alternative: no deal or no Brexit at all".
The risk for May is that if she is incapable of advancing a credible alternative path to Brexit, that infamous and elusive plan B, then Parliament will take the decision out of her hands. "It's a People's Vote, with the option of keeping the best deal we now have as a member of the European Union".
However, fellow Brexiteer Jacob Rees-Mogg has written in the Daily Telegraph of an effort to "frighten and to gull (people) into acquiescing to a non-Brexit Brexit".
"A People's Vote is a practical way to get out of the constitutional crisis we are in". "I think it's that interest in constituents that MPs need to have in their minds too when they come to vote".
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The tool has been used recently to treat deadly diseases in adults, but not in editing sperm , eggs, or embryos. Scientists discovered in recent years a new way to edit genes that make up a person's DNA throughout the body.
They will propose a single motion opposing May's EU Withdrawal Agreement in a debate at the devolved Scottish parliament Holyrood, which has wide-reaching powers over education, health and a portion of taxes.
"I'm tempted to think the price of coming on one of these trips is asking questions about my future, because they come up every time and my answers aren't going to change".
Voters need "clarity" about whether, by ruling out the backstop arrangement which the European Union has demanded to keep the Irish border open after Brexit, Labour is effectively backing the no-deal outcome which the Bank of England this week warned could trigger recession, said the PM.
Brian Monteith, director of communications at Global Britain, accused the prime minister of "selling the country short", slamming her draft deal agreed with Brussels earlier this month. "I've negotiated what I believe truly to be a good deal for the United Kingdom". They say May's Brexit deal was negotiated without taking into account their views, something the government denies.
Mrs May's comments came as International Trade Secretary Liam Fox insisted that a no-deal Brexit would not be a disaster.
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On Tuesday, Trump followed up and reminded the company of its debt to the American people and threatened to slash all subsidies. In 2017 he said high-quality manufacturing jobs were no longer leaving Ohio. "They better put something else in", he said.
And the ex-cabinet minister dismissed the suggestion this would be a "denial of the democratic rights" of the 17.4 million people who voted for Brexit.