In a statement, the Ministry of Foreign Affairs said that systematic attempts to undermine state institutions in Libya are behind such attacks and repeated aggressions in its varied forms and manifestations.
They stormed the foreign ministry headquarters after a auto bomb exploded in front of the building.
One of the two gunmen is believed to have been killed after an explosion was heard in the top floor of the building, politician Guma El-Gamaty who was in the area said.
ISIS storms foreign office in Libya: At least four dead in Tripoli terror attack
The Health Ministry confirmed the death toll and said 10 other people were wounded.
Last month, the group claimed responsibility for an attack on militia forces in southeastern Libya in which at least nine people were killed.
In 2015 a UN-backed deal was signed in Morocco creating the Government of National Accord, in Tripoli, but when Mr Al Sarraj arrived to set up the new administration, Mr Haftar refused to recognise it. He said the foreign ministry had been targeted because "it is a symbol of sovereignty". "It is needed to guarantee security and combat terrorism", Siala told reporters.
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"We will work with the Libyan people to prevent terrorist groups from turning Libya into a haven or an arena for their crimes", he said.
Smoke rises from the site of the headquarters of Libya's foreign ministry after suicide attackers hit in Tripoli, Libya, December 25, 2018.
The United Nations Support Mission in Libya condemned the attack.
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Four months earlier, it claimed an attack on the electoral commission's headquarters that killed 14 people. Later in the day, the Islamic State (IS, formerly ISIS/ISIL) terrorist group claimed responsibility for the attack, through its propaganda outlet. Currently, Libya has two rival governments and a plan to hold a presidential election this year was postponed due to the continuing power struggle.
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Wall Street has suffered the worst start to December since 1980, with stocks showing no sign of recovery before the holidays. Instead of a Santa rally, yesterday saw a Santa crash . "Clearly it's in sharp contrast to last year's optimistic outlook".